Profhilo® is an innovative injectable treatment designed for tissue bio-remodelling and improvement in skin laxity, primarily on the face and neck, but also on the décolleté, hands, arms, knees and abdomen (Profhilo® Body).
What sets it apart is its high concentration of ultrapure hyaluronic acid — 64 mg in 2 ml, equally composed of low and high molecular weight HA. It is thermally stabilised without the use of chemical cross-linking agents (such as BDDE in HA dermal fillers). This unique formulation allows it to flow seamlessly from the injection point, diffusing across anatomical areas for even distribution.
Injected using the Bio Aesthetic Points (BAP) technique, Profhilo® acts as a potent skin stimulator, triggering bio-remodelling and hydration from within.
Indications
- Fine lines and skin laxity
- Dull, dehydrated or crepey skin
- Early signs of ageing on face, neck, and body
- Loss of skin elasticity post-weight loss or post-pregnancy
- Suitable for all skin types
Benefits
✅ Improves skin firmness and elasticity in treated areas
✅ Boosts collagen and elastin production
✅ Restores skin quality without altering facial structure
✅ Suitable for the face, neck, décolletage, and hands
✅ Profhilo® Body available for abdomen, arms, inner thighs, knees
Treatment Protocol
🔹Course: 2 sessions, spaced 4 weeks apart
🔹Maintenance: Recommended every 4 – 6 months
🔹Downtime: Minimal—mild redness, swelling, or small bumps at injection points may
occur and usually resolve within 24–48 hours
Contraindications▼
- Under 18 years of age, pregnant or breastfeeding.
- Known allergy to hyaluronic acid or Profhilo® components.
- History of keloid scarring.
- Ongoing skin infections, eczema, or psoriasis at treatment site.
- Severe uncontrolled medical conditions (e.g., diabetes).
- Active systemic infection (e.g., hepatitis, HIV).
- Currently undergoing cancer treatment or recent history of skin cancer at treatment site.
- Use of anticoagulants or blood disorders increasing bruising risk (e.g., thrombocytopenia).
- Allergy to local anaesthetics (lidocaine, articaine) if used.
Pre-Treatment Advice▼
- Avoid aspirin, ibuprofen, alcohol, and blood-thinning supplements (fish oils, St John's Wort, vitamins A/E) for 48 hours prior.
- No aesthetic or dental treatments within 2 weeks before treatment.
- Discontinue use of retinoids (e.g., tretinoin, adapalene) 5 days prior to reduce skin irritation.
- No steroid medication (e.g., prednisone) 3 weeks before treatment.
- Do not attend your appointment if you feel unwell or have any signs of infection.
- Arrive with a clean face – no make-up or skincare products.
- Be well hydrated on the day of treatment.
Post-Treatment Advice▼
- Avoid touching or massaging treated areas for 6 hours.
- After 6 hours, you may gently cleanse with a mild product; sterile make-up can be applied.
- Avoid heat exposure (hot showers, steam rooms, saunas, sunbeds), strenuous exercise and swimming until swelling subsides.
- No alcohol for 24–48 hours after treatment.
- Use broad-spectrum SPF 50+ daily for at least 5 days post-treatment.
- Avoid aesthetic, dental or vaccine appointments for 14 days post-treatment.
- Refrain from retinoids (e.g., tretinoin, adapalene) for 5 days post-treatment.
- No make-up for 24 hours; avoid acids or exfoliants for 48 hours.
- Stay well hydrated to support healing and skin hydration.
- If redness, swelling, tenderness or nodules persist, contact your practitioner promptly.
Profhilo® Structura
Profhilo® Structura redefines facial structure and support addressing age related fat compartment atrophy. It was designed for deeper structural remodelling clinically proven to reposition and regenerate the dynamic superficial fat pads.
Its advanced compatibility with fat cells helps counteract the flattening of facial angles and tissue descent that naturally occurs over time, resulting in a more lifted, contoured and rejuvenated facial profile.
The aging process simplified effects the bone, muscles, tissues and skin of the face, these changes take place in different areas of the face at varying times, onset at different ages for each person.
With age the volume and structure of adipose tissue change
As time progresses, the face undergoes various changes, generally resulting in two predominant ageing profiles:
Profile 1:
Thinner skin and less density in tissues
Hollow in the cheeks
Bones become more visible, especially around the temples and under the cheekbones
Profile 2:
Skin feels thicker and firmer overall
More volume tends to gather in lower areas
Skin and tissue loose support causing increased sagging and drooping
Profhilo® Structura offers a tailored approach based on these facial aging patterns with two different protocols and techniques. Once injected Profhilo® Structura activates ageing adipose fat cell receptors and encouraging them to mimic the behaviour of their youth.
The result is a more lifted, naturally contoured profile without obvious projections or the appearance of artificial enhancements.
Profhilo® Structura is clinically proven to restore superficial fat to its original position, effectively tackling age related concerns like pronounced facial hollows, skin laxity and the development of a squarer facial shape resulting from mid face fat loss.
Benefits
✅ Improves skin firmness and mechanical strength
✅ Targets deeper dermal tissue remodelling
✅ Suitable for areas experiencing volume loss or significant laxity (e.g. cheeks,
temples, jawline)
✅ Stimulates fibroblasts and keratinocytes for collagen and elastin production
✅ Enhances skin architecture and elasticity over time
✅ Provides a lifting effect without adding volume like fillers
✅ Complements the original Profhilo® for deeper structural support
Treatment Protocol
🔹 Course: 2 treatments 4 weeks apart
🔹 Results: Initial improvements visible within 1–2 days, with progressive improvement
over 4 weeks
🔹 Maintenance: Every 4–10 months (patient dependent)
🔹 Downtime: Minimal; patients can resume daily activities shortly after
Contraindications▼
- Under 18 years of age, pregnant or breastfeeding.
- Known allergy to hyaluronic acid or Profhilo® components.
- History of keloid scarring.
- Ongoing skin infections, eczema, or psoriasis at treatment site.
- Severe uncontrolled medical conditions (e.g., diabetes).
- Active systemic infection (e.g., hepatitis, HIV).
- Currently undergoing cancer treatment or recent history of skin cancer at treatment site.
- Use of anticoagulants or blood disorders increasing bruising risk (e.g., thrombocytopenia).
- Allergy to local anaesthetics (lidocaine, articaine) if used.
Pre-Treatment Advice▼
- Avoid aspirin, ibuprofen, alcohol, and blood-thinning supplements (fish oils, St John's Wort, vitamins A/E) for 48 hours prior.
- No aesthetic or dental treatments within 2 weeks before treatment.
- Discontinue use of retinoids (e.g., tretinoin, adapalene) 5 days prior to reduce skin irritation.
- No steroid medication (e.g., prednisone) 3 weeks before treatment.
- Do not attend your appointment if you feel unwell or have any signs of infection.
- Arrive with a clean face – no make-up or skincare products.
- Be well hydrated on the day of treatment.
Post-Treatment Advice▼
- Avoid touching or massaging treated areas for 6 hours.
- After 6 hours, you may gently cleanse with a mild product; sterile make-up can be applied.
- Avoid heat exposure (hot showers, steam rooms, saunas, sunbeds), strenuous exercise and swimming until swelling subsides.
- No alcohol for 24–48 hours after treatment.
- Use broad-spectrum SPF 50+ daily for at least 5 days post-treatment.
- Avoid aesthetic, dental or vaccine appointments for 14 days post-treatment.
- Refrain from retinoids (e.g., tretinoin, adapalene) for 5 days post-treatment.
- No make-up for 24 hours; avoid acids or exfoliants for 48 hours.
- Stay well hydrated to support healing and skin hydration.
- If redness, swelling, tenderness or nodules persist, contact your practitioner promptly.
Donovan House
The Long Walk
Dundalk
Co. Louth
085 8566865
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