Radiesse®, developed by German manufacturer Merz Aesthetics, is an advanced biostimulator designed to regenerate the skin from within by stimulating the body’s natural collagen and elastin production.
Works by supporting the skin’s structure while triggering long-term regenerative processes
Encourages the skin to rebuild strength, density, and resilience over time
Radiesse® can be used in different ways,
depending on the treatment goal - from improving skin quality and firmness to restoring structure where volume has been lost.
The latest development in skin-quality biostimulation
Radiesse® Hyperdilute, also known as a Radiesse® Wash, represents an advanced technique in skin-quality biostimulation. This is a specialised treatment technique focused entirely on improving skin quality - without adding volume at any stage.
In this approach, Radiesse® is diluted or hyperdiluted depending on the treatment area, allowing for smooth, even distribution within the skin. Unlike other applications of Radiesse®, the Wash technique is not intended to lift, contour, or reshape. Its sole purpose is to stimulate collagen and elastin production, leading to gradual improvements in skin firmness, texture, and elasticity.
Radiesse® Hyperdilute is particularly suited to larger or delicate areas affected by skin laxity, thinning, and crepiness, where structural support or volumisation would be inappropriate.
How Radiesse® Hyperdilute Works
Radiesse® Hyperdilute works through pure biostimulation:
Results develop gradually over the following weeks as the skin regenerates from within.
Benefits of Radiesse® Hyperdilute
✅ Improves skin firmness, elasticity, and texture
✅ Stimulates natural collagen and elastin production
✅ Strengthens and tightens crepey or lax skin
✅ Enhances skin quality without adding volume
✅ Gradual, natural-looking results
✅ Suitable for larger or delicate treatment areas
✅ Non-surgical and minimally invasive
✅ Biocompatible and CE-marked
Common Treatment Areas for Radiesse® Hyperdilute
Radiesse® Hyperdilute may be used to improve skin quality in areas such as:
Treatment plans, including dilution and technique, are tailored to the individual patient and treatment area.
Treatment Technique
Due to the size of the treatment areas and the need for even product distribution, Radiesse® Hyperdilute is typically administered using a microcannula. This allows for smoother placement, reduced trauma, and optimal skin coverage.
Biostimulation with structural support
In its standard application, Radiesse® is used as a biostimulator that also provides structural support in areas affected by volume loss and reduced skin density.
Radiesse® has a unique dual-action mechanism:
- Immediate Volume Effect
• The gel carrier provides instant structure and lift
• Smooths wrinkles and restores facial or hand contours right after injection
- Biostimulation Phase
• The CaHA microspheres stimulate your body to produce new collagen (neocollagenesis)
• Triggers natural regeneration within the skin's deeper layers
- Collagen Remodelling (over the following weeks and months):
• The gel carrier is slowly absorbed
• Types I and III collagen are synthesised
• Skin becomes firmer, denser, and more elastic
This approach is suited to patients who require both regeneration and structural reinforcement, rather than skin-quality improvement alone.
Benefits
✅ Instant volume restoration
✅ Stimulates collagen and elastin production for longer-term firmness
✅ Results last 12–18 months in most patients
✅ Versatile applications - face, jawline, neck, hands, and more
✅ Non-surgical and minimally invasive
✅ Natural-looking results - enhances, not alters your features
✅ Biocompatible and safe - made of materials found naturally in the body
✅ CE-marked and widely used internationally
Treatment Protocol
🔹Course: 1 session (occasionally 2)
A second session may be considered in cases of:
🔹Maintenance:
Typically considered around 12 months, depending on the treatment area, baseline skin condition, and individual response.
🔹Downtime: Minimal recovery - most resume normal activity within 24 hours
Temporary effects may include:
