Profhilo® Structura redefines facial structure and support addressing age related fat compartment atrophy. It was designed for deeper structural remodelling clinically proven to reposition and regenerate the dynamic superficial fat pads.

Its advanced compatibility with fat cells helps counteract the flattening of facial angles and tissue descent that naturally occurs over time, resulting in a more lifted, contoured and rejuvenated facial profile.

 

The aging process simplified effects the bone, muscles, tissues and skin of the face, these changes take place in different areas of the face at varying times, onset at different ages for each person.

 

 

With age the volume and structure of adipose tissue change

 

 

 

As time progresses, the face undergoes various changes, generally resulting in two predominant ageing profiles:

 Profile 1:

 

Thinner skin and less density in tissues

Hollow in the cheeks

Bones become more visible, especially around the temples and under the cheekbones

 

Profile 2:

 

Skin feels thicker and firmer overall

More volume tends to gather in lower areas

Skin and tissue loose support causing increased sagging and drooping

 

Profhilo® Structura offers a tailored approach based on these facial aging patterns with two different protocols and techniques. Once injected Profhilo® Structura activates ageing adipose fat cell receptors and encouraging them to mimic the behaviour of their youth.

The result is a more lifted, naturally contoured profile without obvious projections or the appearance of artificial enhancements.

Profhilo® Structura is clinically proven to restore superficial fat to its original position, effectively tackling age related concerns like pronounced facial hollows, skin laxity and the development of a squarer facial shape resulting from mid face fat loss.

 

Benefits

 

  Improves skin firmness and mechanical strength

  Targets deeper dermal tissue remodelling

  Suitable for areas experiencing volume loss or significant laxity (e.g. cheeks, 

       temples, jawline)

  Stimulates fibroblasts and keratinocytes for collagen and elastin production

  Enhances skin architecture and elasticity over time

  Provides a lifting effect without adding volume like fillers

  Complements the original Profhilo® for deeper structural support

 

 

Treatment Protocol

 

🔹 Course: 2 treatments 4 weeks apart

🔹 Results: Initial improvements visible within 1–2 days, with progressive improvement 

      over 4 weeks

🔹  Maintenance: Every 4–10 months (patient dependent)

🔹  Downtime: Minimal; patients can resume daily activities shortly after

 

Contraindications
  • Under 18 years of age, pregnant or breastfeeding.
  • Known allergy to hyaluronic acid or Profhilo® components.
  • History of keloid scarring.
  • Ongoing skin infections, eczema, or psoriasis at treatment site.
  • Severe uncontrolled medical conditions (e.g., diabetes).
  • Active systemic infection (e.g., hepatitis, HIV).
  • Currently undergoing cancer treatment or recent history of skin cancer at treatment site.
  • Use of anticoagulants or blood disorders increasing bruising risk (e.g., thrombocytopenia).
  • Allergy to local anaesthetics (lidocaine, articaine) if used.
Pre-Treatment Advice
  • Avoid aspirin, ibuprofen, alcohol, and blood-thinning supplements (fish oils, St John's Wort, vitamins A/E) for 48 hours prior.
  • No aesthetic or dental treatments within 2 weeks before treatment.
  • Discontinue use of retinoids (e.g., tretinoin, adapalene) 5 days prior to reduce skin irritation.
  • No steroid medication (e.g., prednisone) 3 weeks before treatment.
  • Do not attend your appointment if you feel unwell or have any signs of infection.
  • Arrive with a clean face – no make-up or skincare products.
  • Be well hydrated on the day of treatment.
Post-Treatment Advice
  • Avoid touching or massaging treated areas for 6 hours.
  • After 6 hours, you may gently cleanse with a mild product; sterile make-up can be applied.
  • Avoid heat exposure (hot showers, steam rooms, saunas, sunbeds), strenuous exercise and swimming until swelling subsides.
  • No alcohol for 24–48 hours after treatment.
  • Use broad-spectrum SPF 50+ daily for at least 5 days post-treatment.
  • Avoid aesthetic, dental or vaccine appointments for 14 days post-treatment.
  • Refrain from retinoids (e.g., tretinoin, adapalene) for 5 days post-treatment.
  • No make-up for 24 hours; avoid acids or exfoliants for 48 hours.
  • Stay well hydrated to support healing and skin hydration.
  • If redness, swelling, tenderness or nodules persist, contact your practitioner promptly.