Bio-Plasma-Gel-Filler-Dundalk

Introduction

Bio Plasma Gel Filler is an autologous treatment that restores facial volume and softens fine lines by transforming your own blood plasma into a smooth, gel-like filler rich in albumin and growth factors. After centrifugation the plasma is heated and cooled to create the gel, which is then mixed with injectable platelet-rich fibrin (i-PRF) to enhance tissue regeneration and results. This fully autologous, biocompatible, and minimally processed gel provides immediate volume and stimulates natural tissue response [3]. Typically, one session produces approximately 4 – 6 ml of Bio Plasma Gel Filler, enough to treat multiple facial areas. Like all autologous treatments, results improve progressively over time as your tissue responds naturally [1][2].

Benefits

✅ Excellent cell bio compatibility and safety profile as autologous

✅ Natural alternative to synthetic fillers

✅ Adds instant volume in treated areas
✅ Softens fine lines and wrinkles through gentle tissue support
✅ Enhances skin texture and elasticity in treated areas

✅ Strengthens the skin's barrier function
✅ Ideal for clients sensitive to synthetic fillers

✅ For patients allergic to Hyaluronidase (HA filler Dissolvent)
✅ Very low risk of allergic reactions

✅ Promotes cellular regeneration and skin health

Indications

Mid-face volume loss (cheeks, jawline, chin)
Nasolabial folds and marionette lines
Tear trough hollowing and dark under-eye circles
Fine lines, recessed scars, or crepey skin texture
Early signs of skin laxity

📊 Clinical Insight:

A 2024 study reported 30–50% wrinkle score improvement with autologous plasma gel in nasolabial folds, with high satisfaction and minimal downtime [5].

Treatment Protocol

🔹 Sessions: 2/3 treatments, spaced 6 – 8 weeks apart

🔹Volume per session: approximately 4 – 6 ml of Bio Plasma Gel Filler available per treatment
🔹 Duration: Approximately ca. 60 minutes
🔹 Results:

Immediate volume
Progressive improvement over 1 – 3 months as tissue responds naturally
Lasting ca. 12 months, depending on individual factors

🔹 Maintenance: Recommended every 9 – 12 months

Downtime & Safety

Downtime: Minimal
Possible mild side effects:

Swelling, redness, bruising, itching at injection sites
Minor bruising at venepuncture
Headache or tenderness

Rare risks: localised inflammation, granuloma, nerve irritation [1][2][5]

References

Doghaim, N. N., et al. (2021). Autologous plasma gel as a volume filler: Preparation and applications. Clinical, Cosmetic and Investigational Dermatology, 14, 1367–1375.
Neinaa, Y. M., et al. (2020). Evaluation of Autologous Plasma Gel in Tear Trough Deformity. Journal of Cosmetic Dermatology.
Niigata University (2023). Plasma Gel (PG): Heating method and growth factor retention. Biomedicines, 11(11), 2871.
Karimi, K. (2022). Natural, Regenerative and Bio-Stimulating Gel Set to Revolutionize Facial Rejuvenation. The Aesthetic Guide, June 2022.
Hassani, N., Jurdan, M., et al. (2024). Multi-centric Clinical Study of Autologous Plasma Gel in Correction of the Nasolabial Folds. Journal of Regenerative Medicine.

Contraindications▼

Not suitable for under 18s, pregnant, or breastfeeding women.
No history of skin cancer or active cancer treatment at treatment site.
No anticoagulation therapy or blood disorders (e.g., thrombocytopenia, severe coagulopathies).
No active skin infections or dermatological conditions (e.g., eczema, psoriasis) at treatment site.
No severe metabolic or systemic disorders (e.g., uncontrolled diabetes).
No allergy to local anaesthetics (topical or injectable, e.g., lidocaine, articaine).
No known allergy to treatment components (e.g., plasma derivatives, saline).
No history of keloid scarring.
No active systemic infections (e.g., hepatitis, HIV).

Pre-Treatment Advice▼

Avoid blood thinners (e.g., aspirin, ibuprofen), alcohol, supplements (e.g., fish oils, vitamins A–E) for 72 hours prior to ensure optimal platelet function.
No systemic steroids (e.g., prednisone) for 3 weeks prior.
No dental treatments, aesthetic treatments, or vaccines 2 weeks prior.
Avoid retinol or retinoid products (e.g., tretinoin, adapalene) for 5 days prior to reduce skin irritation.
Ensure no active infections; consult a doctor if recent illness is suspected.

Post-Treatment Advice▼

Avoid massaging or pressuring treated areas for 48 hours.
Avoid heat (e.g., hot showers, saunas, sun, intense exercise) for 48 hours to minimize swelling/bruising.
No alcohol for 48 hours.
No aesthetic treatments, vaccines, or dental treatments for 2 weeks post-treatment.
Avoid retinol or retinoid products (e.g., tretinoin, adapalene) for 5 days post-treatment to support healing.
Avoid makeup for 24 hours; use gentle skincare (no acids, AHAs) for 48 hours.
Avoid washing treated area for 24 hours to allow growth factors or plasma components to settle.
Monitor for signs of infection (e.g., redness, swelling, pain) and contact practitioner if present.

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